10 Best b6 pyridoxal phosphates of 2026

Explore top picks

Best Choice

1

THORNE
THORNE - Pyridoxal 5'-Phosphate - Bioactive Vitamin B6 (Pyridoxine) Supplement for Energy Production and Neurotransmitter Synthesis* - 180 Capsules
Main highlights

Key Features
Active form of Vitamin B6 for optimal absorption, supports amino acid synthesis and neurotransmitter production, free from major allergens.

Ideal Use Cases
Perfect for women with PMS when paired with magnesium, and individuals seeking enhanced brain health and neurotransmitter support.

Customer Praise
Highly praised for its effectiveness in alleviating PMS symptoms and improving mood, with noticeable benefits in overall wellness.
Key specs
- Formulation:Vitamin B6
- Dietary Restrictions:No gluten, soy, dairy
- Support For:PMS support
- Dosage:N/A
- Serving Size:N/A
9.8

Exceptional

Our Rating

9.9
simple to consume

9.9
Flavor

9.3
worth the money
How do we rank?

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Value for Money

2

Designs for Health

Designs for Health P-5-P - 50mg Vitamin B6 (P5P Pyridoxal-5-Phosphate) Supplement - Non-GMO, Vegan B-6 (120 Capsules)
9.5

Excellent

Our Rating
3

Life Extension

Life Extension Pyridoxal 5'-Phosphate Caps—Vitamin B6, 100 mg, Bioactive B6 for Cardiovascular, Kidney & Nerve Health—Gluten-Free, Non-GMO, Vegetarian—60 Vegetarian Capsules
9.4

Excellent

Our Rating
4

Nutricost
Nutricost P5P Vitamin B6 Supplement 50mg, 240 Capsules (Pyridoxal-5-Phosphate) - Vegetarian Friendly, Non-GMO, Gluten Free
Main highlights

Key Features and Benefits
Contains 50mg P5P per capsule for 240 servings, promoting optimal Vitamin B6 levels. Vegetarian, non-GMO, gluten-free, made in a GMP compliant, FDA registered facility.

Ideal Use Cases
Perfect for those seeking to support their nervous system, boost metabolism, and improve mood through a high-quality, bioavailable form of Vitamin B6.

Customer Reviews Highlight
Most praised for its effectiveness in improving energy levels and mood, with noticeable benefits in neurological and metabolic health.
9.3

Excellent

Our Rating

9.9
worth the money

9.9
simple to consume

9.9
quality of ingredients
5

Horbäach
Horbäach P5P Activated Vitamin B6 100mg | 120 Tablets | Vegetarian Supplement, Non-GMO, Gluten Free | Pyridoxal 5 Phosphate | Coenzyme B6
Main highlights

Premium Quality and Value
P-5-P is a high-quality, metabolically active form of vitamin B-6, providing exceptional value with 100 mg per serving in an easy-to-take vegetarian formula.

Ideal for Neuropathy Relief
This product is particularly beneficial for individuals experiencing neuropathy, especially those looking to switch from the HCL form of B-6 to P-5-P for better results.

Effective Neuropathy Improvement
Customers frequently praise the significant improvement in neuropathy symptoms, with many noting measurable progress verified by doctor visits after consistent use.
Key specs
- Formulation:Tablets
- Dietary Restrictions:Gluten, Wheat, Non-GMO
- Support For:Vitamin B-6
- Dosage:Two tablets
- Serving Size:100 mg
9.2

Excellent

Our Rating

9.3
quality of ingredients

8.7
simple to consume

8.2
worth the money
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6

BulkSupplements

BulkSupplements.com Pyridoxal 5 Phosphate Capsules - P5P Supplement, Vitamin B6 Supplement - Essential & Gluten Free, 1 Capsule per Serving, 500 Count (Pack of 1)
9.0

Excellent

Our Rating
7

Nutricost
Nutricost P5P Vitamin B6 Supplement 100mg, 240 Capsules (Pyridoxal-5-Phosphate) - Vegetarian Friendly, Non-GMO, Gluten Free
Main highlights

Key Features
100mg P5P per capsule, 240 servings, supports vitamin B6 levels. Vegetarian, Non-GMO, Gluten-Free, made in GMP compliant, FDA registered facility.

Ideal Use Cases
Perfect for those needing to boost vitamin B6 intake, vegetarians, and people with dietary restrictions. Supports metabolism and nervous system health.

Customer Praise
Most reviews highlight its effectiveness in improving energy levels and mood, and appreciate the product`s purity and high manufacturing standards.
Key specs
- Formulation:Vitamin B6 Supplement
- Dietary Restrictions:Vegetarian Friendly
- Support For:N/A
- Dosage:100mg Of P5P
- Serving Size:1 Capsule
8.9

Very Good

Our Rating

9.9
simple to consume

9.9
worth the money

9.9
Flavor
8

Best Naturals
Best Naturals P5P Vitamin B6 (Pyridoxal 5 Phosphate) 100 mg/Serving - 120 Tablets - an Active Form of Vitamin B6.
Main highlights

Key Features
High-quality P5P formula supports nervous system health and healthy homocysteine levels. 3rd party lab-tested, made in the USA with no artificial additives.

Ideal Use Cases
Best for individuals seeking to maintain nervous system health and manage homocysteine levels, especially those with dietary restrictions.

Customer Praise
Most reviews highlight the product`s effectiveness in improving health outcomes and appreciate its purity and lack of allergens.
Key specs
- Formulation:Pyridoxal 5 Phosphate
- Dietary Restrictions:No Gluten, No Soy
- Support For:Nervous System Health
- Dosage:N/A
- Serving Size:N/A
8.8

Very Good

Our Rating

9.1
worth the money

8.4
simple to consume

8.4
Flavor
9

Seeking Health
Seeking Health P-5-P (Pyridoxal 5-Phosphate) - Immune Health & Homocysteine Metabolism Support - Support Energy Production with Bioavailable Vitamin B6-25, 100 Capsules
Main highlights

Targeted Support Benefits
Provides 25 mg of vitamin B6, supporting pregnancy, protein metabolism, brain function, cognitive development, homocysteine metabolism, and immune system function.

Ideal for Vegans and Vegetarians
Suitable for those who may not receive adequate B6 levels without animal food sources, ensuring easily absorbed and bioavailable supplementation.

Highly Absorbable and Effective
Praised for its small capsule size, high bioavailability, and significant energy-boosting effects, making it a preferred choice for many users.
8.5

Good

Our Rating

9.9
simple to consume

9.7
quality of ingredients

8.0
worth the money
10

Think Above

Think Above P5P Liquid Drops – Activated Vitamin B6 (Pyridoxal-5-Phosphate) – Fast Absorption Formula – Nervous System & Energy Support – 2 oz (60 mL)
8.4

Good

Our Rating

10 Best b6 pyridoxal phosphates of 2026

1

THORNE - Pyridoxal 5'-Phosphate - Bioactive Vitamin B6 (Pyridoxine) Supplement for Energy Production and Neurotransmitter Synthesis* - 180 Capsules

9.9

9.9

9.3

How do we rank?

How do we rank?

Analyzing top stores

2

Designs for Health P-5-P - 50mg Vitamin B6 (P5P Pyridoxal-5-Phosphate) Supplement - Non-GMO, Vegan B-6 (120 Capsules)

3

Life Extension Pyridoxal 5'-Phosphate Caps—Vitamin B6, 100 mg, Bioactive B6 for Cardiovascular, Kidney & Nerve Health—Gluten-Free, Non-GMO, Vegetarian—60 Vegetarian Capsules

4

Nutricost P5P Vitamin B6 Supplement 50mg, 240 Capsules (Pyridoxal-5-Phosphate) - Vegetarian Friendly, Non-GMO, Gluten Free

9.9

9.9

9.9

5

Horbäach P5P Activated Vitamin B6 100mg | 120 Tablets | Vegetarian Supplement, Non-GMO, Gluten Free | Pyridoxal 5 Phosphate | Coenzyme B6

9.3

8.7

8.2

6

BulkSupplements.com Pyridoxal 5 Phosphate Capsules - P5P Supplement, Vitamin B6 Supplement - Essential & Gluten Free, 1 Capsule per Serving, 500 Count (Pack of 1)

7

Nutricost P5P Vitamin B6 Supplement 100mg, 240 Capsules (Pyridoxal-5-Phosphate) - Vegetarian Friendly, Non-GMO, Gluten Free

9.9

9.9

9.9

8

Best Naturals P5P Vitamin B6 (Pyridoxal 5 Phosphate) 100 mg/Serving - 120 Tablets - an Active Form of Vitamin B6.

9.1

8.4

8.4

9

Seeking Health P-5-P (Pyridoxal 5-Phosphate) - Immune Health & Homocysteine Metabolism Support - Support Energy Production with Bioavailable Vitamin B6-25, 100 Capsules

9.9

9.7

8.0

10

Think Above P5P Liquid Drops – Activated Vitamin B6 (Pyridoxal-5-Phosphate) – Fast Absorption Formula – Nervous System & Energy Support – 2 oz (60 mL)

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