September 14, 2025

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10 Best any killer sprays of 2025

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1

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Ortho
Ortho Home Defense Insect Killer for Indoor and Perimeter2 with Comfort Wand, Controls Ants, Roaches, Spiders and More, 1.33 gal

20% Off
Main highlights

Key Features
Offers 12-month protection against a wide range of bugs, non-staining, odor-free, with a convenient one-touch continuous spray Comfort Wand.

Ideal Use Cases
Perfect for homes needing long-term defense against ants, roaches, spiders, and more on nonporous surfaces without the hassle of frequent reapplication.

Customer Praise
Most reviews highlight the effectiveness in eliminating pests quickly and the ease of use of the Comfort Wand, appreciating the no mess application.
9.7

Exceptional

Our Rating

9.9
Easy to build

8.4
Simple to use

8.2
Easy installation
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Shoppers influence our rankings
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Value for Money

2

Mighty Mint
Mighty Mint Peppermint Oil Ant Killer Spray – Natural Ant Repellent for Indoor & Outdoor Use – Plant-Based Insect & Pest Control – 16 oz
Main highlights

Safe Natural Ingredients
Utilizes peppermint oil to repel ants safely around pets and people.

Versatile Indoor Outdoor Use
Effective for all ant types, ideal for home and garden use.

Highly Praised Mint Scent
Fresh mint scent is pleasant and doesn't linger long.
9.5

Excellent

Our Rating

8.9
Simple to use

8.2
Aroma

8.0
worth the money
3

Raid
Raid Ant & Roach Killer 26, Fragrance Free Bug Killer for Home Use, Kills Bugs on Contact, 17.5 Oz, 2 Count

10% Off
Main highlights

Chemical-Free Freshness
Eliminates pests without unpleasant chemical scents; leaves an outdoor fresh aroma.

Multi-Pest Protection
Ideal for indoor and outdoor use; effective against ants, roaches, spiders, and more.

Customer Praised Scent
Customers love the minimal scent, perfect for enclosed spaces.
9.4

Excellent

Our Rating

9.3
Simple to use

9.1
worth the money

9.1
Aroma
4

STEM
STEM Kills Ants, Roaches And Flies: Plant-Based Active Ingredient Bug Spray, Botanical Insecticide For Indoor And Outdoor Use; 12 fl oz (Pack Of 1)
Main highlights

Plant-Based Safety and Effectiveness
Natural bug spray with plant-based ingredients, safe for pets and kids.

Versatile Indoor and Outdoor Use
Ideal for use in homes and gardens, effective on ants, roaches, and flies.

Customer Praised Quick Kill Action
Highly effective in killing bugs on contact with minimal application.
Key specs
- Application Type:Spray
- Target Pests:Ants, roaches, flies
- Use Location:Indoor and outdoor
- Active Ingredient:Plant-based
- Effect Duration:N/A
9.3

Excellent

Our Rating

8.9
Simple to use

8.0
worth the money

8.0
Aroma
5

Spectracide
Spectracide Bug Stop Home Barrier, Kills Ants, Roaches and Spiders On Contact, Indoor and Outdoor Insect Control, 32 fl Ounce Ready-To-Use Spray
Main highlights

Instant Insect Control
Spectracide Bug Stop kills ants, roaches, and spiders instantly, providing immediate relief from pests.

Versatile Home Protection
Ideal for indoor and outdoor use, maintaining a bug-free environment throughout your home.

Customer Satisfaction
Users praise its effectiveness in eliminating ants and other pests with high ratings.
9.0

Excellent

Our Rating

8.4
Simple to use

8.0
worth the money
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6

Ortho
Ortho Home Defense Insect Killer for Indoor and Perimeter Refill2, Controls Ants, Roaches, Spiders and More, 1 gal

20% Off
Main highlights

Comprehensive Insect Control
Ortho Home Defense kills ants, roaches, spiders, and more.

Versatile Use
Ideal for indoor kitchens, bathrooms, and outdoor patios.

Highly Effective Barrier
Customers praise its ability to eliminate and prevent bugs.
Key specs
- product dimensions:4.9 x 9 x 12.12 inches
- refill cartridges:Home Defense Insect Killer
- usage:Indoor & outdoor pest control
- country of origin:USA
- safety:N/A
8.9

Very Good

Our Rating

9.9
Precision

9.7
worth the money

9.7
Simple to use
7

HOT SHOT
Hot Shot Ant, Roach & Spider Killer, Kills Insects Indoors and Outdoors, Kills Roaches and Listed Ants on Contact, Insecticide Spray, 17.5 Ounce (Crisp Linen)
Main highlights

Fast Knockdown Insecticide
Kills insects on contact and provides up to 3 months of protection.

Indoor and Outdoor Versatility
Ideal for use both indoors and outdoors against common household pests.

Effective Contact Kill
Praised for its immediate effectiveness and pleasant scent in customer reviews.
Key specs
- Application Type:Spray
- Target Pests:Ants, cockroaches, spiders
- Use Location:Indoors, outdoors
- Active Ingredient:N/A
- Effect Duration:Up to 3 months
8.8

Very Good

Our Rating

8.7
Simple to use

8.4
worth the money

8.0
Aroma
8

Raid
Raid Essentials Multi-Insect Killer Spray Bottle, Child and Pet Safe, for Indoor Use, Lemongrass Scent, 12 fl oz
Main highlights

Safe and Effective
Raid Essentials Multi-Insect Killer is safe around children and pets, using essential oils to kill insects effectively.

Ideal for Indoor Use
Perfect for use around the home, especially in areas prone to insect activity like door frames and kitchens.

Highly Praised Scent and Safety
Customers appreciate its lemongrass scent and safety for pets, despite a lingering odor.
Key specs
- Application Type:Spray
- Target Pests:Roaches, Ants, Mosquitos
- Use Location:Around the home
- Active Ingredient:Essential oils
- Effect Duration:N/A
8.7

Very Good

Our Rating

9.9
worth the money

9.9
Simple to use

8.2
Aroma
9

Terro
TERRO T401SR Indoor and Outdoor Ant Killer Aerosol Spray - Kills Ants, Cockroaches, Crickets, Scorpions, Spiders, and Other Insects - 2 Pack 32 Total Ounces
Main highlights

Versatile Indoor and Outdoor Use
The TERRO T401SR is effective both indoors and outdoors, providing flexibility in pest control.

Ideal for Multiple Insect Types
Perfect for tackling ants, cockroaches, spiders, and more, ensuring comprehensive insect control.

Highly Praised Contact Kill Effectiveness
Customers love its ability to kill insects on contact, making it a reliable pest solution.
8.6

Very Good

Our Rating

9.3
Simple to use

9.3
Easy to use

8.9
worth the money
10

Raid

Raid Flying Insect Killer 7, Insecticide Spray with Outdoor Fresh Scent, 18 fl oz
8.5

Good

Our Rating

10 Best any killer sprays of 2025

1

Ortho Home Defense Insect Killer for Indoor and Perimeter2 with Comfort Wand, Controls Ants, Roaches, Spiders and More, 1.33 gal

9.9

8.4

8.2

How do we rank?

How do we rank?

Analyzing top stores

2

Mighty Mint Peppermint Oil Ant Killer Spray – Natural Ant Repellent for Indoor & Outdoor Use – Plant-Based Insect & Pest Control – 16 oz

8.9

8.2

8.0

3

Raid Ant & Roach Killer 26, Fragrance Free Bug Killer for Home Use, Kills Bugs on Contact, 17.5 Oz, 2 Count

9.3

9.1

9.1

4

STEM Kills Ants, Roaches And Flies: Plant-Based Active Ingredient Bug Spray, Botanical Insecticide For Indoor And Outdoor Use; 12 fl oz (Pack Of 1)

8.9

8.0

8.0

5

Spectracide Bug Stop Home Barrier, Kills Ants, Roaches and Spiders On Contact, Indoor and Outdoor Insect Control, 32 fl Ounce Ready-To-Use Spray

8.4

8.0

6

Ortho Home Defense Insect Killer for Indoor and Perimeter Refill2, Controls Ants, Roaches, Spiders and More, 1 gal

9.9

9.7

9.7

7

Hot Shot Ant, Roach & Spider Killer, Kills Insects Indoors and Outdoors, Kills Roaches and Listed Ants on Contact, Insecticide Spray, 17.5 Ounce (Crisp Linen)

8.7

8.4

8.0

8

Raid Essentials Multi-Insect Killer Spray Bottle, Child and Pet Safe, for Indoor Use, Lemongrass Scent, 12 fl oz

9.9

9.9

8.2

9

TERRO T401SR Indoor and Outdoor Ant Killer Aerosol Spray - Kills Ants, Cockroaches, Crickets, Scorpions, Spiders, and Other Insects - 2 Pack 32 Total Ounces

9.3

9.3

8.9

10

Raid Flying Insect Killer 7, Insecticide Spray with Outdoor Fresh Scent, 18 fl oz

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