10 Best any killer sprays of 2025

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Ortho
Ortho Home Defense Insect Killer for Indoor and Perimeter2 with Comfort Wand, Controls Ants, Roaches, Spiders and More, 1.33 gal

15% Off
Main highlights

Key Features
Offers 12-month protection against a wide range of bugs, non-staining, odor-free, with a convenient one-touch continuous spray Comfort Wand.

Ideal Use Cases
Perfect for homes needing long-term defense against ants, roaches, spiders, and more on nonporous surfaces without the hassle of frequent reapplication.

Customer Praise
Most reviews highlight the effectiveness in eliminating pests quickly and the ease of use of the Comfort Wand, appreciating the no mess application.
9.7

Exceptional

Our Rating

9.9
Easy to build

8.4
Simple to use

8.2
Easy installation
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Value for Money

2

Ortho
Ortho Home Defense Max Indoor Insect Barrier with Extended Reach Comfort Wand, Kills Ants, Roaches, Spiders, Fleas and Ticks, 1 gal.
Main highlights

12-Month Protection
Provides up to 12 months of control for ants, roaches, and spiders indoors.

Ideal for Indoor Use
Perfect for kitchens, bathrooms, and basements to prevent insect entry.

User-Friendly Application
Praised for its easy-to-use wand that reduces bending and fatigue.
9.6

Exceptional

Our Rating

8.2
Easy to build

8.0
Simple to use

8.0
Aroma
3

Raid
Raid Ant & Roach Killer 26, Fragrance Free Bug Killer for Home Use, Kills Bugs on Contact, 17.5 Oz, 2 Count
Main highlights

Chemical-Free Freshness
Eliminates pests without unpleasant chemical scents; leaves an outdoor fresh aroma.

Multi-Pest Protection
Ideal for indoor and outdoor use; effective against ants, roaches, spiders, and more.

Customer Praised Scent
Customers love the minimal scent, perfect for enclosed spaces.
9.5

Excellent

Our Rating

9.3
Simple to use

9.1
worth the money

9.1
Aroma
4

STEM
STEM Kills Ants, Roaches And Flies: Plant-Based Active Ingredient Bug Spray, Botanical Insecticide For Indoor And Outdoor Use; 12 fl oz (Pack Of 1)
Main highlights

Plant-Based Safety and Effectiveness
Natural bug spray with plant-based ingredients, safe for pets and kids.

Versatile Indoor and Outdoor Use
Ideal for use in homes and gardens, effective on ants, roaches, and flies.

Customer Praised Quick Kill Action
Highly effective in killing bugs on contact with minimal application.
Key specs
- Application Type:Spray
- Target Pests:Ants, roaches, flies
- Use Location:Indoor and outdoor
- Effect Duration:N/A
- Active Ingredient:Plant-based
9.4

Excellent

Our Rating

8.9
Simple to use

8.0
worth the money

8.0
Aroma
5

Ortho

Ortho Home Defense Max Ant, Roach and Spider1: Indoor Insect Spray, Kills Ants, Beetles, Cockroaches and Spiders (as Listed), No Fumes, 14 oz.

11% Off
9.1

Excellent

Our Rating
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6

Raid
Raid Essentials Multi-Insect Killer Spray Bottle, Child and Pet Safe, for Indoor Use, Lemongrass Scent, 12 fl oz
Main highlights

Safe and Effective
Raid Essentials Multi-Insect Killer is safe around children and pets, using essential oils to kill insects effectively.

Ideal for Indoor Use
Perfect for use around the home, especially in areas prone to insect activity like door frames and kitchens.

Highly Praised Scent and Safety
Customers appreciate its lemongrass scent and safety for pets, despite a lingering odor.
Key specs
- Application Type:Spray
- Target Pests:Roaches, Ants, Mosquitos
- Use Location:Around the home
- Effect Duration:N/A
- Active Ingredient:Essential oils
9.0

Excellent

Our Rating

9.9
worth the money

9.9
Simple to use

8.2
Aroma
7

Raid

Raid Ant & Roach Killer Spray For Listed Bugs, Keeps Killing for Weeks, Lemon Scent, 17.5 oz

11% Off
8.8

Very Good

Our Rating
8

Spectracide
Spectracide Bug Stop Home Barrier Spray, Kills Ants, Roaches and Spiders On Contact, Indoor and Outdoor Insect Control, 1.33 Gallon
Main highlights

Kills Multiple Insects
This product kills ants, roaches, spiders, fleas, ticks, and more both indoors and outdoors with a fast-acting, non-staining, clear formula.

Effective Indoors and Outdoors
Ideal for use in cracks, crevices, baseboards, sinks, stoves, refrigerators, screens, doors, window frames, porches, patios, and building exteriors.

Highly Praised for Ant Control
Customers frequently praise its effectiveness in keeping ants away, with many noting significant reduction in ant presence around their homes.
Key specs
- Application Type:Indoors and outdoors
- Target Pests:Ants, roaches, spiders
- Use Location:Indoors and outdoors
- Effect Duration:Kills on contact
- Active Ingredient:N/A
8.7

Very Good

Our Rating

9.5
Simple to use

9.3
worth the money

9.1
Long life
9

HOT SHOT
Hot Shot Ant, Roach & Spider Killer, Kills Insects Indoors and Outdoors, Kills Roaches and Listed Ants on Contact, Insecticide Spray, 17.5 Ounce (Crisp Linen)
Main highlights

Fast Knockdown Insecticide
Kills insects on contact and provides up to 3 months of protection.

Indoor and Outdoor Versatility
Ideal for use both indoors and outdoors against common household pests.

Effective Contact Kill
Praised for its immediate effectiveness and pleasant scent in customer reviews.
Key specs
- Application Type:Spray
- Target Pests:Ants, cockroaches, spiders
- Use Location:Indoors, outdoors
- Effect Duration:Up to 3 months
- Active Ingredient:N/A
8.6

Very Good

Our Rating

8.7
Simple to use

8.4
worth the money

8.0
Aroma
10

Spectracide
Spectracide Bug Stop Home Barrier 32 Ounces, Ready-To-Use Indoor Plus Outdoor Insect Control
Main highlights

Instant Insect Control
Spectracide Bug Stop kills ants, roaches, and spiders instantly, providing immediate relief from pests.

Versatile Home Protection
Ideal for indoor and outdoor use, maintaining a bug-free environment throughout your home.

Customer Satisfaction
Users praise its effectiveness in eliminating ants and other pests with high ratings.
8.4

Good

Our Rating

8.4
Simple to use

8.0
worth the money

10 Best any killer sprays of 2025

1

Ortho Home Defense Insect Killer for Indoor and Perimeter2 with Comfort Wand, Controls Ants, Roaches, Spiders and More, 1.33 gal

9.9

8.4

8.2

How do we rank?

How do we rank?

Analyzing top stores

2

Ortho Home Defense Max Indoor Insect Barrier with Extended Reach Comfort Wand, Kills Ants, Roaches, Spiders, Fleas and Ticks, 1 gal.

8.2

8.0

8.0

3

Raid Ant & Roach Killer 26, Fragrance Free Bug Killer for Home Use, Kills Bugs on Contact, 17.5 Oz, 2 Count

9.3

9.1

9.1

4

STEM Kills Ants, Roaches And Flies: Plant-Based Active Ingredient Bug Spray, Botanical Insecticide For Indoor And Outdoor Use; 12 fl oz (Pack Of 1)

8.9

8.0

8.0

5

Ortho Home Defense Max Ant, Roach and Spider1: Indoor Insect Spray, Kills Ants, Beetles, Cockroaches and Spiders (as Listed), No Fumes, 14 oz.

6

Raid Essentials Multi-Insect Killer Spray Bottle, Child and Pet Safe, for Indoor Use, Lemongrass Scent, 12 fl oz

9.9

9.9

8.2

7

Raid Ant & Roach Killer Spray For Listed Bugs, Keeps Killing for Weeks, Lemon Scent, 17.5 oz

8

Spectracide Bug Stop Home Barrier Spray, Kills Ants, Roaches and Spiders On Contact, Indoor and Outdoor Insect Control, 1.33 Gallon

9.5

9.3

9.1

9

Hot Shot Ant, Roach & Spider Killer, Kills Insects Indoors and Outdoors, Kills Roaches and Listed Ants on Contact, Insecticide Spray, 17.5 Ounce (Crisp Linen)

8.7

8.4

8.0

10

Spectracide Bug Stop Home Barrier 32 Ounces, Ready-To-Use Indoor Plus Outdoor Insect Control

8.4

8.0

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