10 Best antifungal creams for dogs of 2025

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Best Choice

1

Douxo S3
Douxo S3 Pyo Mousse, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, for Bacterial or Yeast Skin Infections, for Dogs, 5.1 fl. oz. (150mL)
Main highlights

Hydration and Skin Support
Proven to hydrate skin and support healing with ophytrium.

Ideal for Skin Conditions
Best for dogs and cats with skin infections or hot spots.

Ease of Use
Pump mousse consistency praised for easy application.
Key specs
- Volume:7.05 ounces
- Formulation:Mousse
- Ingredients:Ophytrium
- Features:Hydrates skin, soap-free
- pH Balanced:N/A
9.8

Exceptional

Our Rating

9.5
Comfort

9.3
Simple to use

9.1
For Gentle skin
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Value for Money

2

Nootie
Nootie Medicated Dog Wipes - Antifungal Wipes - Antibacterial Wipes - Antimicrobial Wipes for Dogs 2% Chlorhexidine Wipes with 2% Micronazole for Best Results with Cats and Dogs Problems 60 pads - USA, White
Main highlights

Veterinarian Strength Relief
Contains Chlorhexidine and Miconazole for effective skin and ear relief.

Ideal for Skin Conditions
Perfect for treating ringworm, hotspots, and allergy dermatitis.

Convenience Praised by Users
Easy to use with low odor, appreciated for quick application.
9.7

Exceptional

Our Rating

9.3
Simple to use

8.7
worth the money

8.4
Aroma
3

Veterinary Formula

Veterinary Formula Clinical Care Antiseptic and Antifungal Medicated Spray for Dogs & Cats, 8 Fl Oz (1 Pack)

43% Off
9.5

Excellent

Our Rating
4

Sulfodene
Sulfodene Dog Wound Care 3-Way Ointment, Relieves Pain & Prevents Infection For Dog Cuts, Scrapes, Bites and Injuries, 2 Ounce

22% Off
Main highlights

Pain Relief and Infection Prevention
First aid dog ointment relieves pain and prevents infection, ensuring your pet's comfort and health.

Versatile Use for Dog Injuries
Ideal for cuts, scrapes, bites, abrasions, and skin irritations, providing comprehensive wound care.

Positive Customer Feedback on Effectiveness
Praised for quick healing and reducing itching, enhancing pet comfort and owner satisfaction.
Key specs
- Target Condition:Cuts, scrapes, bites
- Supports Healing:Prevents infection
- Formulation:Ointment
- Usage Instructions:Consult a veterinarian
- Application:External use only
9.2

Excellent

Our Rating

9.1
pain management

8.9
Simple to use

8.7
worth the money
5

Smiling Paws Pets
Smiling Paws Pets - Antibacterial & Antifungal Wipes for Dogs & Cats (with Chlorhexidine & Ketoconazole)
Main highlights

Effective Treatment for Skin Infections
Combines Ketoconazole & Chlorhexidine to eliminate yeast, fungi, and bacteria.

Ideal for Hard-to-Reach Areas
Small, thin wipes fit easily into crevices like paws.

Praised for Quick Relief
Users report rapid alleviation of symptoms in pets.
Key specs
- Use Case:Skin infections treatment
- Ingredients:Ketoconazole, Chlorhexidine, Aloe
- Dimensions:2.5 x 2.5 inches
- Cleaning Method:Wipes
- Pack Size:N/A
9.1

Excellent

Our Rating

9.1
Simple to use

8.7
Aroma

8.7
Flavor
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6

MED PRIDE
MED PRIDE 1% Clotrimazole Antifungal Cream 1oz- Fungus Skin Care Treatment with - Jock Itch Body Ointment - Fights Infection, Sweat Rash, Athletes Foot, Ringworm & Relieves Itching, Burning
Main highlights

Effective Antifungal Treatment
MED PRIDE Clotrimazole Cream effectively treats jock itch, athlete's foot, and ringworm, providing relief from itching and burning sensations.

Ideal for Regular Use
Perfect for occasional or preventive use, especially in warm weather to prevent fungal infections.

Praised for Affordability and Effectiveness
Customers appreciate its effectiveness comparable to top brands at a lower price.
9.0

Excellent

Our Rating
7

Globe Pharmacy
Globe Clotrimazole Antifungal Cream 1% USP (1 oz), Anti Fungal Treatment, Relieves Itching, Burning, Cracking and Scaling Associated Athletes Foot, Jock Itch, Ringworm and More
Main highlights

Effective_Treatment_for_Common_Fungal_Infections
Globe Clotrimazole Cream effectively treats athlete's foot, jock itch, and ringworm, providing relief from itching, burning, cracking, and scaling.

Ideal_for_Heat_Related_Rashes_and_Fungal_Issues
Perfect for treating rashes and fungal infections caused by heat and moisture, ensuring comfort and quick recovery.

Affordable_Alternative_to_Name_Brand
Customers appreciate its affordability and effectiveness compared to leading brands, offering the same active ingredients.
Key specs
- product dimensions:5 x 2 x 5 inches
- active ingredient:Clotrimazole
- country of origin:USA
- formulation:Cream
- usage instructions:N/A
8.8

Very Good

Our Rating

9.1
Simple to use

8.9
worth the money

8.4
Aroma
8

Zymox
Zymox Veterinarian Strength Topical Cream with 1% Hydrocortisone for Dogs and Cats, 1oz
Main highlights

Gentle_Relief_for_Skin_Irritations
Provides soothing relief from itchy skin, hot spots, and dermatitis.

Ideal_for_Face_Paws_and_Body_Folds
Perfect for treating skin irritations in sensitive areas like face and paws.

Praised_for_Quick_Results
Customers appreciate its ability to quickly reduce irritation and itching.
Key specs
- Usage:Skin irritations relief
- Size:1 x 1 x 5 inches
- Cleaning Method:No pre-cleaning required
- Special Features:Soothing relief, no-sting
- Color:N/A
8.7

Very Good

Our Rating

9.9
Aroma

9.7
Simple to use

9.5
Comfort
9

Paw Science

Paw Science Antibacterial & Antifungal Medicated Wipes for Dogs and Cats – 100 Count - Chlorhexidine Wipes with Ketoconazole for The Treatment of Rashes, Skin Infections, Itchy Paws, and Pet Acne
8.5

Good

Our Rating
10

Globe
Globe Miconazole Nitrate 2% Antifungal Cream 1 oz, Cures Most Athletes Foot, Jock Itch, Ringworm and More. Compare to the Leading Name Brand

55% Off
Main highlights

Effective Antifungal Treatment
Contains 2% Miconazole, effectively treating athlete's foot, jock itch, and ringworm.

Ideal for Skin Irritations
Perfect for relieving itching, burning, and scaling on feet and body.

Quick and Reliable Results
Praised for fast relief and resolving skin issues efficiently.
Key specs
- product dimensions:5 x 1 x 1 inches
- active ingredient:Miconazole 2%
- country of origin:USA
- formulation:Cream
- usage instructions:Apply twice daily
8.4

Good

Our Rating

9.3
quality of ingredients

8.9
pain management

8.7
worth the money

10 Best antifungal creams for dogs of 2025

1

Douxo S3 Pyo Mousse, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, for Bacterial or Yeast Skin Infections, for Dogs, 5.1 fl. oz. (150mL)

9.5

9.3

9.1

How do we rank?

How do we rank?

Analyzing top stores

2

Nootie Medicated Dog Wipes - Antifungal Wipes - Antibacterial Wipes - Antimicrobial Wipes for Dogs 2% Chlorhexidine Wipes with 2% Micronazole for Best Results with Cats and Dogs Problems 60 pads - USA, White

9.3

8.7

8.4

3

Veterinary Formula Clinical Care Antiseptic and Antifungal Medicated Spray for Dogs & Cats, 8 Fl Oz (1 Pack)

4

Sulfodene Dog Wound Care 3-Way Ointment, Relieves Pain & Prevents Infection For Dog Cuts, Scrapes, Bites and Injuries, 2 Ounce

9.1

8.9

8.7

5

Smiling Paws Pets - Antibacterial & Antifungal Wipes for Dogs & Cats (with Chlorhexidine & Ketoconazole)

9.1

8.7

8.7

6

MED PRIDE 1% Clotrimazole Antifungal Cream 1oz- Fungus Skin Care Treatment with - Jock Itch Body Ointment - Fights Infection, Sweat Rash, Athletes Foot, Ringworm & Relieves Itching, Burning

7

Globe Clotrimazole Antifungal Cream 1% USP (1 oz), Anti Fungal Treatment, Relieves Itching, Burning, Cracking and Scaling Associated Athletes Foot, Jock Itch, Ringworm and More

9.1

8.9

8.4

8

Zymox Veterinarian Strength Topical Cream with 1% Hydrocortisone for Dogs and Cats, 1oz

9.9

9.7

9.5

9

Paw Science Antibacterial & Antifungal Medicated Wipes for Dogs and Cats – 100 Count - Chlorhexidine Wipes with Ketoconazole for The Treatment of Rashes, Skin Infections, Itchy Paws, and Pet Acne

10

Globe Miconazole Nitrate 2% Antifungal Cream 1 oz, Cures Most Athletes Foot, Jock Itch, Ringworm and More. Compare to the Leading Name Brand

9.3

8.9

8.7

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