10 Best anti itch sprays of 2025

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Best Choice

1

Cortizone 10

Cortizone-10 Maximum Strength Soothing Aloe Itch Relief Cooling Spray, 1% Hydrocortisone, Fast-Acting, Anti-Itch Spray for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac, 2.7 oz 3-Pack
9.7

Exceptional

Our Rating
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Value for Money

2

Benadryl

Benadryl Cooling Anti-Itch Spray 2 fl. Oz and Benadryl Extra Strength Itch Relief Stick 0.47 fl. oz, Both with Diphenhydramine 1 ea
9.6

Exceptional

Our Rating
3

Cortizone 10
Cortizone 10 Maximum Strength Soothing Aloe Itch Relief Cooling Spray, 1% Hydrocortisone, Fast-Acting, Anti-Itch Spray for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac, 2.7 oz
Main highlights

Fast Relief and Cooling
Provides fast-acting relief with a cooling mist for itch and irritation.

Versatile Use Cases
Ideal for insect bites, rashes, eczema, psoriasis, and poison ivy.

Praised Application Method
Customers love the upside-down spray feature for hard-to-reach areas.
Key specs
- form:Spray
- size:2.7 oz
- active ingredient:Hydrocortisone 1
- application method:Spray
- skin conditions:Inflammation, rashes, eczema
9.5

Excellent

Our Rating
4

Benadryl

Benadryl Extra Strength Itch Cooling Spray, Topical Analgesic Spray with Diphenhydramine HCI & Zinc Acetate Skin Protectant for Fast Relief from Insect Bites, Travel Size, 2 fl. oz
9.4

Excellent

Our Rating

9.9
pain management

9.7
Simple to use

9.5
Easy to grip
5

Bactine MAX
Bactine Max Pain Relieving Antiseptic Spray with Lidocaine, First Aid Pain + Itch Relief, No-Sting, Kills 99% of Germs*, 5oz
Main highlights

Max Relief and Germ Protection
Bactine MAX provides pain and itch relief while killing 99% of germs.

Ideal for Minor Injuries
Perfect for cuts, scrapes, burns, bug bites, and sunburns.

No-Sting Application Praised
Customers appreciate the sting-free application, even on sensitive skin.
9.3

Excellent

Our Rating

9.7
Simple to use

9.3
pain management

8.7
Easy to grip
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6

Dermoplast
Dermoplast Pain, Burn & Itch Relief Spray for Minor Cuts, Burns and Bug Bites, 2.75 Oz (Packaging May Vary)

13% Off
Main highlights

Fast Pain and Itch Relief
Dermoplast provides quick relief from minor cuts, burns, and bug bites with hospital-strength Benzocaine.

Ideal for Postpartum and Family Use
Perfect for postpartum care and soothing children's minor injuries, offering no-touch application.

Highly Effective and Easy to Use
Customers praise its instant cooling effect and versatility for various skin irritations.
9.2

Excellent

Our Rating

9.7
Simple to use

9.1
worth the money

8.9
pain management
7

Dermoplast

Dermoplast Pain, Burn & Itch Relief Spray for Minor Cuts, Burns and Bug Bites, 2.75 Oz, Pack of 2 (Packaging May Vary)
9.0

Excellent

Our Rating
8

Tecnu
Tecnu Rash Relief Medicated Anti Itch Spray with Scar Prevention, 6 Fl Oz, Protection & Itchy Skin Relief from Poison Ivy, Poison Oak, Rashes, Insect Bites & Sunburn, Homeopathic Skin Care
Main highlights

Immediate Relief and Scar Prevention
Offers quick relief from itching and promotes healing without scarring.

Versatile Outdoor Use
Ideal for insect bites, poison ivy, and minor burns—perfect for outdoor enthusiasts.

Highly Effective Itch Stopper
Customers praise its ability to stop itching quickly and effectively.
Key specs
- Application Method:Spray
- Type of Relief:Pain & itching relief
- Formulation:Homeopathic formula
- Usage Instructions:Spray on affected area
- Product Dimensions:2 x 2 x 6.25 inches
8.9

Very Good

Our Rating

9.5
Comfort

9.1
Simple to use

8.2
worth the money
9

NeilMed
NeilMed Anti Itch (Relief) Spray Hydrocortisone 1%, 3 Oz
Main highlights

Fast Acting Itch Relief
NeilMed Anti Itch Relief Spray provides quick relief from itching due to insect bites, poison ivy, and skin irritations.

Versatile Application
Ideal for outdoor enthusiasts, this spray offers easy application for insect bites and rashes.

Spray at Any Angle
Customers love its ability to spray at any angle, making application easy and effective.
Key specs
- form:Spray
- size:4.64 ounces
- active ingredient:Hydrocortisone 1
- application method:Spray
- skin conditions:Insect bites, rashes
8.8

Very Good

Our Rating
10

MUHU

MUHU Equate Maximum Strength Anti-Itch Continuous Spray, 4.0 oz, 4 Ounce (Pack of 1)

19% Off
8.6

Very Good

Our Rating

10 Best anti itch sprays of 2025

1

Cortizone-10 Maximum Strength Soothing Aloe Itch Relief Cooling Spray, 1% Hydrocortisone, Fast-Acting, Anti-Itch Spray for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac, 2.7 oz 3-Pack

How do we rank?

How do we rank?

Analyzing top stores

2

Benadryl Cooling Anti-Itch Spray 2 fl. Oz and Benadryl Extra Strength Itch Relief Stick 0.47 fl. oz, Both with Diphenhydramine 1 ea

3

Cortizone 10 Maximum Strength Soothing Aloe Itch Relief Cooling Spray, 1% Hydrocortisone, Fast-Acting, Anti-Itch Spray for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac, 2.7 oz

4

Benadryl Extra Strength Itch Cooling Spray, Topical Analgesic Spray with Diphenhydramine HCI & Zinc Acetate Skin Protectant for Fast Relief from Insect Bites, Travel Size, 2 fl. oz

9.9

9.7

9.5

5

Bactine Max Pain Relieving Antiseptic Spray with Lidocaine, First Aid Pain + Itch Relief, No-Sting, Kills 99% of Germs*, 5oz

9.7

9.3

8.7

6

Dermoplast Pain, Burn & Itch Relief Spray for Minor Cuts, Burns and Bug Bites, 2.75 Oz (Packaging May Vary)

9.7

9.1

8.9

7

Dermoplast Pain, Burn & Itch Relief Spray for Minor Cuts, Burns and Bug Bites, 2.75 Oz, Pack of 2 (Packaging May Vary)

8

Tecnu Rash Relief Medicated Anti Itch Spray with Scar Prevention, 6 Fl Oz, Protection & Itchy Skin Relief from Poison Ivy, Poison Oak, Rashes, Insect Bites & Sunburn, Homeopathic Skin Care

9.5

9.1

8.2

9

NeilMed Anti Itch (Relief) Spray Hydrocortisone 1%, 3 Oz

10

MUHU Equate Maximum Strength Anti-Itch Continuous Spray, 4.0 oz, 4 Ounce (Pack of 1)

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