10 Best anti itch creams of 2025

Save up to 48% off

Best Choice

1

CeraVe

CeraVe Moisturizing Cream for Itch Relief, Anti Itch Cream with Pramoxine Hydrochloride, Relieves Itchy with Minor Skin Irritations, Sunburn Relief, Bug Bites, Fragrance Free, 16 Ounces

17% Off
9.7

Exceptional

Our Rating
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Value for Money

2

CeraVe
CeraVe Anti Itch Moisturizing Lotion with Pramoxine Hydrochloride, Relieves Itch with Minor Skin Irritations, Sunburn Relief, Bug Bites, 8 Ounce
Main highlights

Fast-Acting Relief
Provides quick relief from itching due to insect bites, sunburn, and poison ivy, while moisturizing skin.

Versatile Use
Ideal for minor skin irritations, dry skin, and occasional itchy patches.

Moisturizing Benefit
Highly praised for combining itch relief with effective skin hydration.
9.4

Excellent

Our Rating

9.1
Moisturizing

8.9
Aroma

8.9
Comfort
3

Cortizone 10
Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 2 oz.
Main highlights

Maximum Strength Relief
Contains 1% hydrocortisone for fast, effective itch relief.

Ideal for Itch and Irritation
Perfect for eczema, psoriasis, insect bites, and rashes.

Praised for Quick Absorption
Non-greasy formula absorbs quickly, leaving no residue.
9.3

Excellent

Our Rating
4

Amazon Basic Care
Amazon Basic Care Maximum Strength Anti-Itch Cream, Hydrocortisone 1 Percent Intensive Healing Formula, Itch Relief For Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac, 1 ounce (Pack of 1)

16% Off
Main highlights

Maximum Strength Relief
Contains hydrocortisone 1% for fast, effective itch relief.

Versatile Use Cases
Ideal for bug bites, eczema, psoriasis, and poison ivy.

Highly Praised Value
Works as well as name brands at a lower price.
9.1

Excellent

Our Rating

9.9
quality of ingredients

9.7
Moisturizing

9.1
Aroma
5

Benadryl
Benadryl Extra Strength Anti-Itch Topical Cream with 2% Diphenhydramine HCI for Itch Relief of Outdoor Itches Associated with Poison Ivy, Insect Bites & More, 1 fl oz

26% Off
Main highlights

Effective Relief for Itching and Pain
Benadryl Extra Strength Anti-Itch Cream offers fast relief from itching and pain caused by insect bites, sunburn, and other minor skin irritations.

Ideal for Outdoor Enthusiasts
Perfect for camping, hiking, and other outdoor activities, providing on-the-go relief for common outdoor itches.

Highly Praised for Quick Itch Relief
Customers appreciate the cream's ability to quickly alleviate itching from mosquito and other insect bites.
9.0

Excellent

Our Rating

9.5
pain management

8.9
Simple to use

8.2
worth the money
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6

Cortizone 10
Cortizone 10 Maximum Strength Intensive Moisture Anti-Itch Cream, 1% Hydrocortisone, 2 oz.
Main highlights

Maximum Strength Itch Relief
Cortizone-10 provides fast relief from itch with maximum-strength hydrocortisone and nourishing moisturizers.

Ideal for Minor Skin Irritations
Perfect for relieving itch from dry, chafed, and chapped skin.

Instant Relief and No Grease
Highly praised for its quick action and non-greasy feel.
8.9

Very Good

Our Rating
7

CeraVe
CeraVe 1% Hydrocortisone Anti-Itch Cream, Fragrance-Free Relief for Eczema-Prone & Dry Skin, 1 Ounce
Main highlights

Maximum Itch Relief with Hydrocortisone
Provides temporary relief from itchiness due to dry skin and minor irritations.

Ideal for Eczema-Prone and Dry Skin
Formulated with hydrating ingredients like Hyaluronic Acid and Niacinamide.

Non-Greasy and Fragrance-Free
Praised for its non-greasy texture and absence of fragrance.
8.6

Very Good

Our Rating

9.1
Aroma

8.9
Moisturizing

8.9
Comfort
8

Globe
Globe (4 Pack) Hydrocortisone Maximum Strength Anti-Itch Cream 1% w/Aloe, Intensive Formula for Redness, Rash, Bug & Mosquito Bites, Eczema, Hemorrhoids, Sensitive Skin, Instant Itch Relief,1 oz Tube

48% Off
Main highlights

Maximum Strength Relief with Aloe
Combines hydrocortisone 1% with aloe vera for soothing, moisturizing relief.

Versatile Home and Travel Use
Effective for skin irritations, rashes, insect bites, and more.

Great Value and Quantity
Affordable multi-pack praised for its convenience and cost-effectiveness.
8.5

Good

Our Rating
9

Benadryl
Benadryl Anti Itch Gel, Relief of Outdoor Itches Associated with Poison Ivy, Topical Analgesic, Cooling Relief, Diphenhydramine, 3.5 oz

25% Off
Main highlights

Fast-Acting Cooling Relief
Benadryl Extra Strength Gel provides quick relief from itching and pain caused by insect bites, sunburn, and minor skin irritations.

Outdoor Activity Essential
Ideal for camping, hiking, and outdoor events, offering relief for ages 2 and up.

Instant Itch Control
Customers praise its immediate itch relief and cooling sensation, making it a must-have for skin irritations.
8.3

Good

Our Rating

8.7
Simple to use

8.4
worth the money

8.4
For traveling
10

Cortizone 10
Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 1 oz.
Main highlights

Maximum Strength Itch Relief
Cortizone 10 provides fast relief with hydrocortisone and soothing aloe.

Ideal for Eczema and Skin Irritations
Perfect for eczema, psoriasis, and poison plant reactions.

Highly Effective for Mosquito Bites
Customers praise its effectiveness on mosquito bites.
8.2

Good

Our Rating

8.7
worth the money

8.2
Aroma

8.0
Moisturizing

10 Best anti itch creams of 2025

1

CeraVe Moisturizing Cream for Itch Relief, Anti Itch Cream with Pramoxine Hydrochloride, Relieves Itchy with Minor Skin Irritations, Sunburn Relief, Bug Bites, Fragrance Free, 16 Ounces

How do we rank?

How do we rank?

Analyzing top stores

2

CeraVe Anti Itch Moisturizing Lotion with Pramoxine Hydrochloride, Relieves Itch with Minor Skin Irritations, Sunburn Relief, Bug Bites, 8 Ounce

9.1

8.9

8.9

3

Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 2 oz.

4

Amazon Basic Care Maximum Strength Anti-Itch Cream, Hydrocortisone 1 Percent Intensive Healing Formula, Itch Relief For Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac, 1 ounce (Pack of 1)

9.9

9.7

9.1

5

Benadryl Extra Strength Anti-Itch Topical Cream with 2% Diphenhydramine HCI for Itch Relief of Outdoor Itches Associated with Poison Ivy, Insect Bites & More, 1 fl oz

9.5

8.9

8.2

6

Cortizone 10 Maximum Strength Intensive Moisture Anti-Itch Cream, 1% Hydrocortisone, 2 oz.

7

CeraVe 1% Hydrocortisone Anti-Itch Cream, Fragrance-Free Relief for Eczema-Prone & Dry Skin, 1 Ounce

9.1

8.9

8.9

8

Globe (4 Pack) Hydrocortisone Maximum Strength Anti-Itch Cream 1% w/Aloe, Intensive Formula for Redness, Rash, Bug & Mosquito Bites, Eczema, Hemorrhoids, Sensitive Skin, Instant Itch Relief,1 oz Tube

9

Benadryl Anti Itch Gel, Relief of Outdoor Itches Associated with Poison Ivy, Topical Analgesic, Cooling Relief, Diphenhydramine, 3.5 oz

8.7

8.4

8.4

10

Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 1 oz.

8.7

8.2

8.0

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