10 Best acne treatment differin gels of 2026

Explore top picks

Best Choice

1

Differin
Differin Adapalene Gel 0.1% Acne Treatment, 45 gram, 180-day supply, 1.6 Ounce (Pack of 2)
Main highlights

Key Features
Rx-strength retinoid fights acne, regulates skin cell turnover, and reduces inflammation to clear skin and prevent future breakouts.

Ideal Use Cases
Best for individuals struggling with persistent acne, including pimples, blackheads, and clogged pores, seeking clearer, more natural skin tone and texture.

Customer Praise
Highly praised for significantly reducing acne within 12 weeks, with many noting restored skin tone and texture as a standout benefit.
9.8

Exceptional

Our Rating
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Differin

Differin Acne Treatment Gel, 60 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Pack of 2) (Packaging May Vary)
9.7

Exceptional

Our Rating
3

Differin

Differin Acne Treatment Gel, 90 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 45g Pump (Packaging May Vary)
9.5

Excellent

Our Rating

9.1
worth the money

8.7
Aroma

8.0
For Gentle skin
4

Differin

Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Pump (Packaging May Vary)
9.3

Excellent

Our Rating
5

Differin

Differin Acne Skin Care Kit, Differin Gel Retinoid Acne Treatment for Face with 0.1% Adapalene & 5% Benzoyl Peroxide Face Wash & Body Wash, Designed for Pimple and Acne Prone Skin
9.1

Excellent

Our Rating
See Today’s Deals & Prices
6

Differin
Differin Acne Spot Treatment with 10% Benzoyl Peroxide, Maximum Strength OTC Acne Treatment, Fast Acting Spot Treatment for Face, 1 oz
Main highlights

Maximum Strength Treatment
Contains 10% benzoyl peroxide for powerful over-the-counter acne treatment.

Fast Acting Solution
Ideal for quick acne relief, visibly reducing size and redness.

Customer Praised Effectiveness
Highly effective at reducing blemishes quickly with minimal application.
8.8

Very Good

Our Rating
7

Differin

Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne Treatment (Up to 90 Day Supply), 45 Gram
8.7

Very Good

Our Rating
8

TARO
TARO Adapalene 0.1% USP Gel, Paraben Free, Retinoid Acne-Prone Facial Treatment for Sensitive Skin, Prescription Strenght (0.5)
Main highlights

Dermatologist Developed Formula
Adapalene 0.1% gel is oil-free, fragrance-free, and paraben-free, designed for acne treatment.

Effective for Acne and Wrinkles
Ideal for daily use to treat acne and improve skin texture.

Highly Effective Yet Potent
Praised for its strong effectiveness; users recommend gradual introduction to avoid irritation.
Key specs
- Function:Acne Treatment
- Usage:Once Daily
- Ingredients:Adapalene 0.1
- Packaging:4.8 x 1.97 x 1.46 inches
- Texture:Gel - Oil Free
8.4

Good

Our Rating
9

Differin
Differin Gel Acne Scar Spot Treatment for Face, Resurfacing Scar Gel, Gentle Skin Care for Acne Prone Sensitive Skin, 1 Oz (Packaging May Vary)
Main highlights

Promotes Smooth Skin
Formulated with bakuchiol and peptides to improve skin texture and firmness.

Ideal for Sensitive Skin
Gentle, fragrance-free, and non-comedogenic, perfect for daily use on sensitive skin.

Praised for Moisturizing
Customers love its ability to hydrate and soften skin, reducing scars and imperfections.
8.2

Good

Our Rating

9.1
Simple to use

8.7
Aroma

8.2
worth the money
10

Differin

Differin Adapalene Gel 0.1% Acne Treatment, 0.5 Ounces each (Value Pack of 2)
8.0

Good

Our Rating

10 Best acne treatment differin gels of 2026

1

Differin Adapalene Gel 0.1% Acne Treatment, 45 gram, 180-day supply, 1.6 Ounce (Pack of 2)

How do we rank?

How do we rank?

Analyzing top stores

2

Differin Acne Treatment Gel, 60 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Pack of 2) (Packaging May Vary)

3

Differin Acne Treatment Gel, 90 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 45g Pump (Packaging May Vary)

9.1

8.7

8.0

4

Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Pump (Packaging May Vary)

5

Differin Acne Skin Care Kit, Differin Gel Retinoid Acne Treatment for Face with 0.1% Adapalene & 5% Benzoyl Peroxide Face Wash & Body Wash, Designed for Pimple and Acne Prone Skin

6

Differin Acne Spot Treatment with 10% Benzoyl Peroxide, Maximum Strength OTC Acne Treatment, Fast Acting Spot Treatment for Face, 1 oz

7

Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne Treatment (Up to 90 Day Supply), 45 Gram

8

TARO Adapalene 0.1% USP Gel, Paraben Free, Retinoid Acne-Prone Facial Treatment for Sensitive Skin, Prescription Strenght (0.5)

9

Differin Gel Acne Scar Spot Treatment for Face, Resurfacing Scar Gel, Gentle Skin Care for Acne Prone Sensitive Skin, 1 Oz (Packaging May Vary)

9.1

8.7

8.2

10

Differin Adapalene Gel 0.1% Acne Treatment, 0.5 Ounces each (Value Pack of 2)

Sign up and get exclusive special deals