9 Best acne treatments of 2025

Save up to 44% off

Best Choice

1

Differin

Differin Acne Treatment Gel, 90 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 45g Pump (Packaging May Vary)

34% Off
9.8

Exceptional

Our Rating

9.1
worth the money

8.7
Aroma

8.0
For Gentle skin
How do we rank?

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Value for Money

2

Mighty Patch
Mighty Patch™ Original patch from Hero Cosmetics – The #1 Hydrocolloid Acne Pimple Patch for Shrinking Zits and Whiteheads in 1 use; Nighttime Spot Stickers for Face and Skin (36 Count)
Main highlights

Overnight Pimple Treatment
Mighty Patch Original uses hydrocolloid to visibly improve pimples overnight, reducing redness and size.

Best for Night Use
Ideal for overnight use, these patches stay on securely while you sleep.

Customer Praised Adhesion
Customers love the strong adhesion that keeps the patch in place all night.
9.5

Excellent

Our Rating

9.5
Simple to use

9.5
Simple to take off

9.5
Attachment
3

PanOxyl
PanOxyl Acne Foaming Wash Benzoyl Peroxide 10% Maximum Strength Antimicrobial, 5.5 Oz
Main highlights

Maximum Strength Formula
Contains 10% Benzoyl Peroxide, the highest OTC concentration.

Ideal for Acne and Body Odor
Cleans and unclogs pores, effective for acne and BO.

Praised for Clear Skin
Customers love its ability to clear skin quickly.
Key specs
- Key Ingredients:10% Benzoyl peroxide
- Usage:Face, chest, back
- Texture:Foaming
- Cleansing Method:Antimicrobial foaming wash
- Skin Type:N/A
9.3

Excellent

Our Rating

8.9
worth the money

8.7
Sheerness

8.2
For Gentle skin
4

Differin
Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)

20% Off
Main highlights

Effective Acne Treatment
Differin Gel targets clogged pores and inflammation, reducing breakouts and improving skin texture and tone.

Ideal for Acne-Prone Skin
Best for those with acne-prone, sensitive skin needing a gentle retinoid treatment.

Praised for Clear Skin
Customers love its ability to keep skin clear and smooth, even with hormonal or diet-related acne.
9.1

Excellent

Our Rating

8.2
worth the money

8.0
Aroma

8.0
Fashion
5

AcneFree
AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1

31% Off
Main highlights

Maximum Strength Benzoyl Peroxide
Contains 10% benzoyl peroxide for effective acne treatment and redness control.

Ideal for Spot Treatment
Best used for treating individual pimples and mild recurring acne.

Convenient Flip-Cap Design
Praised for its easy-to-use flip-cap that prevents loss and simplifies application.
Key specs
- Skin Benefits:Redness Control
- Formulation:Cream
- Skin Type:N/A
- Application Frequency:N/A
- Exfoliation Type:N/A
8.9

Very Good

Our Rating

9.7
quality of ingredients

8.4
worth the money

8.0
Sheerness
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6

The Ordinary
The Ordinary Salicylic Acid 2% Solution, Acne-Fighting Serum for Blemish-Prone Skin, 1 Fl Oz
Main highlights

Blemish-Reduction Formula
The Ordinary Salicylic Acid 2% Solution targets acne and blemishes effectively.

Ideal for Oily Skin
Best used for oily and blemish-prone skin types.

Customer Praised Clarity
Users frequently commend its ability to clear skin blemishes.
8.6

Very Good

Our Rating
7

THAYERS
Thayers Blemish Clearing Acne Pads, Salicylic Acid Acne Treatment for Face, Pore Reducing, Exfoliating, and Soothing Skincare, Witch Hazel Toner Pads, 60 Ct
Main highlights

Blemish Control with Moisture
Alcohol-free pads clear acne and prevent breakouts while maintaining skin's moisture.

Perfect for Sensitive Skin
Ideal for sensitive, acne-prone skin needing gentle, effective treatment.

Highly Praised for Effectiveness
Customers love its ability to clear acne without over-drying.
8.5

Good

Our Rating

8.9
Aroma

8.7
worth the money

8.4
For Gentle skin
8

Neutrogena
Neutrogena On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube

44% Off
Main highlights

Effective Acne Treatment with Benzoyl Peroxide
.75-ounce tube with 2.5% benzoyl peroxide fights acne gently.

Ideal for Daily Use on Acne-Prone Skin
Use up to three times daily without over-drying.

Praised for Quick and Visible Results
Customers appreciate its effectiveness and quick results.
Key specs
- Skin Type:All skin types
- Formulation:Cream
- Effects:Fights acne
- Niacinamide:N/A
- Hyaluronic Acid:N/A
8.3

Good

Our Rating
9

Clean & Clear
Clean & Clear Persa-Gel 10 Oil-Free Acne Spot Treatment with Maximum Strength 10% Benzoyl Peroxide, Topical Pimple Cream & Gel Medication for Face, Fragrance-Free, 1 fl. oz, 1 Pack

25% Off
Main highlights

Maximum Strength Formula
Contains 10% benzoyl peroxide for effective acne treatment.

Ideal for Spot Treatment
Perfect for inflamed acne bumps and quick results.

Highly Praised for Quick Results
Users report visible reduction in acne overnight.
8.2

Good

Our Rating

9 Best acne treatments of 2025

1

Differin Acne Treatment Gel, 90 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 45g Pump (Packaging May Vary)

9.1

8.7

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

Mighty Patch™ Original patch from Hero Cosmetics – The #1 Hydrocolloid Acne Pimple Patch for Shrinking Zits and Whiteheads in 1 use; Nighttime Spot Stickers for Face and Skin (36 Count)

9.5

9.5

9.5

3

PanOxyl Acne Foaming Wash Benzoyl Peroxide 10% Maximum Strength Antimicrobial, 5.5 Oz

8.9

8.7

8.2

4

Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)

8.2

8.0

8.0

5

AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1

9.7

8.4

8.0

6

The Ordinary Salicylic Acid 2% Solution, Acne-Fighting Serum for Blemish-Prone Skin, 1 Fl Oz

7

Thayers Blemish Clearing Acne Pads, Salicylic Acid Acne Treatment for Face, Pore Reducing, Exfoliating, and Soothing Skincare, Witch Hazel Toner Pads, 60 Ct

8.9

8.7

8.4

8

Neutrogena On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube

9

Clean & Clear Persa-Gel 10 Oil-Free Acne Spot Treatment with Maximum Strength 10% Benzoyl Peroxide, Topical Pimple Cream & Gel Medication for Face, Fragrance-Free, 1 fl. oz, 1 Pack

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