9 Best acne treatments of 2025

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Best Choice

1

La Roche-Posay
La Roche-Posay Effaclar Adapalene Gel 0.1% Acne Treatment, Retinoid Cream, Acne Medication Gel For Blackheads & Whiteheads, Oil Free, Helps Clear And Prevent Blemishes & Clogged Pores
Main highlights

Prescription Strength Acne Treatment
La Roche-Posay Effaclar Adapalene Gel 0.1% effectively clears and prevents acne and clogged pores with prescription-strength retinoid.

Ideal for Acne and Hyperpigmentation
Best suited for individuals struggling with acne, clogged pores, and hyperpigmentation, delivering noticeable improvements in skin clarity and texture.

Rapid Results Praised by Users
Customers frequently highlight its fast-acting nature, clearing acne and reducing hyperpigmentation within weeks of use.
9.9

Exceptional

Our Rating

9.1
Aroma

8.9
worth the money

8.0
Moisturizing
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Value for Money

2

CeraVe
CeraVe Acne Control Gel, 2% Salicylic Acid Treatment With Glycolic Acid + Lactic Acids + Niacniamide, Acne Gel Helps Clear Blemishes Without Over Drying, Alcohol Free & Oil Free, 1.35 Fl Oz

14% Off
Main highlights

Advanced Exfoliation and Hydration
Combines BHA and AHA to clear acne, smooth skin, and maintain moisture.

Ideal for Sensitive and Acne-Prone Skin
Perfect for those seeking gentle yet effective acne treatment.

Unmatched Performance and Affordability
Praised for its effective results and affordable price point.
9.8

Exceptional

Our Rating

8.9
worth the money

8.9
For Gentle skin

8.7
Aroma
3

Differin
Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)
Main highlights

Effective Acne Treatment
Differin Gel targets clogged pores and inflammation, reducing breakouts and improving skin texture and tone.

Ideal for Acne-Prone Skin
Best for those with acne-prone, sensitive skin needing a gentle retinoid treatment.

Praised for Clear Skin
Customers love its ability to keep skin clear and smooth, even with hormonal or diet-related acne.
9.6

Exceptional

Our Rating

8.2
worth the money

8.0
Aroma

8.0
Fashion
4

PanOxyl
PanOxyl Acne Foaming Wash Benzoyl Peroxide 10% Maximum Strength Antimicrobial, 5.5 Oz
Main highlights

Maximum Strength Formula
Contains 10% Benzoyl Peroxide, the highest OTC concentration.

Ideal for Acne and Body Odor
Cleans and unclogs pores, effective for acne and BO.

Praised for Clear Skin
Customers love its ability to clear skin quickly.
9.4

Excellent

Our Rating

8.9
worth the money

8.7
Sheerness

8.2
For Gentle skin
5

AcneFree
AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1

35% Off
Main highlights

Maximum Strength Benzoyl Peroxide
Contains 10% benzoyl peroxide for effective acne treatment and redness control.

Ideal for Spot Treatment
Best used for treating individual pimples and mild recurring acne.

Convenient Flip-Cap Design
Praised for its easy-to-use flip-cap that prevents loss and simplifies application.
9.2

Excellent

Our Rating

9.7
quality of ingredients

8.4
worth the money

8.0
Sheerness
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6

Mighty Patch
Mighty Patch™ Original patch from Hero Cosmetics - Hydrocolloid Acne Pimple Patch for Covering Zits and Blemishes in Face and Skin, Vegan-friendly and Not Tested on Animals (36 Count)
Main highlights

Overnight Pimple Treatment
Mighty Patch Original uses hydrocolloid to visibly improve pimples overnight, reducing redness and size.

Best for Night Use
Ideal for overnight use, these patches stay on securely while you sleep.

Customer Praised Adhesion
Customers love the strong adhesion that keeps the patch in place all night.
9.1

Excellent

Our Rating

9.5
Simple to use

9.5
Simple to take off

9.5
Attachment
7

Neutrogena
Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with Maximum Strength 10% Benzoyl Peroxide Acne Treatment Medication, Pimple Cream for Acne Prone Skin Care, 1 oz

27% Off
Main highlights

Maximum Strength Benzoyl Peroxide
Contains 10% benzoyl peroxide for rapid acne reduction.

Ideal for Stubborn Acne
Perfect for treating stubborn acne on acne-prone skin.

Quick and Effective Results
Praised for reducing acne size and redness within hours.
8.9

Very Good

Our Rating

8.7
Aroma

8.4
Fashion

8.2
worth the money
8

THAYERS
Thayers Blemish Clearing Acne Pads, Salicylic Acid Acne Treatment for Face, Pore Reducing, Exfoliating, and Soothing Skincare, Witch Hazel Toner Pads, 60 Ct

15% Off
Main highlights

Blemish Control with Moisture
Alcohol-free pads clear acne and prevent breakouts while maintaining skin's moisture.

Perfect for Sensitive Skin
Ideal for sensitive, acne-prone skin needing gentle, effective treatment.

Highly Praised for Effectiveness
Customers love its ability to clear acne without over-drying.
8.8

Very Good

Our Rating

8.9
Aroma

8.7
worth the money

8.4
For Gentle skin
9

Neutrogena
Neutrogena On-The-Spot Acne Treatment Gel with Benzoyl Peroxide - Gentle Face Acne Medicine for Acne Prone Skin, 0.75 oz

33% Off
Main highlights

Effective Acne Treatment with Benzoyl Peroxide
.75-ounce tube with 2.5% benzoyl peroxide fights acne gently.

Ideal for Daily Use on Acne-Prone Skin
Use up to three times daily without over-drying.

Praised for Quick and Visible Results
Customers appreciate its effectiveness and quick results.
8.7

Very Good

Our Rating

9 Best acne treatments of 2025

1

La Roche-Posay Effaclar Adapalene Gel 0.1% Acne Treatment, Retinoid Cream, Acne Medication Gel For Blackheads & Whiteheads, Oil Free, Helps Clear And Prevent Blemishes & Clogged Pores

9.1

8.9

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

CeraVe Acne Control Gel, 2% Salicylic Acid Treatment With Glycolic Acid + Lactic Acids + Niacniamide, Acne Gel Helps Clear Blemishes Without Over Drying, Alcohol Free & Oil Free, 1.35 Fl Oz

8.9

8.9

8.7

3

Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)

8.2

8.0

8.0

4

PanOxyl Acne Foaming Wash Benzoyl Peroxide 10% Maximum Strength Antimicrobial, 5.5 Oz

8.9

8.7

8.2

5

AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1

9.7

8.4

8.0

6

Mighty Patch™ Original patch from Hero Cosmetics - Hydrocolloid Acne Pimple Patch for Covering Zits and Blemishes in Face and Skin, Vegan-friendly and Not Tested on Animals (36 Count)

9.5

9.5

9.5

7

Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel with Maximum Strength 10% Benzoyl Peroxide Acne Treatment Medication, Pimple Cream for Acne Prone Skin Care, 1 oz

8.7

8.4

8.2

8

Thayers Blemish Clearing Acne Pads, Salicylic Acid Acne Treatment for Face, Pore Reducing, Exfoliating, and Soothing Skincare, Witch Hazel Toner Pads, 60 Ct

8.9

8.7

8.4

9

Neutrogena On-The-Spot Acne Treatment Gel with Benzoyl Peroxide - Gentle Face Acne Medicine for Acne Prone Skin, 0.75 oz

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