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10 Best acne spot treatments of 2026
Save up to 28% off
Best Choice1
La Roche-Posay9.8Exceptional
La Roche-Posay Effaclar Salicylic Acid Acne Treatment For Face, Mattifying Acne Gel Cream Spot Treatment for Blackheads, Whiteheads & Pores, Prevents New Pimples, Non-Greasy, Sensitive Skin Safe
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Value for Money2
medicube9.6Exceptional
medicube 3H Overnight Drying Lotion | Targeted Spot Care for Troubled & Oily-Prone Skin | Calming & Soothing Care with Calamine, Centella & Tea Tree | Korean Skincare 20ml, 0.67 fl. oz.
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3
Neutrogena9.4Excellent
Neutrogena Rapid Clear Stubborn Acne Spot Treatment Gel, Maximum Strength 10% Benzoyl Per-oxide Treatment Medication for Acne Prone Skin, Pimple Cream Reduces Size & Redness, 1 oz
28% Off-
is discontinued by manufacturer:No
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upc:070501024614
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asin:B00NR1YVYU
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item model number:70501024614
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manufacturer:Kenvue
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4
AcneFree9.2Excellent
AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1
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is discontinued by manufacturer:No
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product dimensions:4.57 x 1.45 x 3.74 inches; 1 ounces
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upc:850004234785
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asin:B0014VTOAQ
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department:unisex-adult
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5
Differin8.9Very Good
Differin Acne Spot Treatment with 10% Benzoyl Peroxide, Maximum Strength OTC Acne Treatment, Fast Acting Spot Treatment for Face, 1 oz
16% Off-
upc:302994611003
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package dimensions:6.5 x 2.6 x 1.65 inches 1.59 ounces
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asin:B0D355W5F2
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item model number:0299.053078
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manufacturer:Galderma
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6
CeraVe8.8Very Good
CeraVe Acne Control Gel, 2% Salicylic Acid Treatment With Glycolic Acid + Lactic Acids + Niacniamide, Acne Gel Helps Clear Blemishes Without Over Drying, Alcohol Free & Oil Free, 1.35 Fl Oz
15% Off-
asin:B097WMCYYJ
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product dimensions:1.22 x 1.77 x 6.34 inches 1.35 ounces
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item model number:S4584800
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manufacturer:CeraVe
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is discontinued by manufacturer:N/A
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7
Mighty Patch8.7Very Good
Mighty Patch Original Patch from Hero Cosmetics - #1 Hydrocolloid Acne Pimple Patches for Face, Shrinking Zits & Whiteheads in 1 Use, Nighttime Spot Pimple Stickers for Face, 36 Count
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is discontinued by manufacturer:No
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product dimensions:5.5 x 3.25 x 0.75 inches; 0.8 ounces
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upc:864475000404
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asin:B074PVTPBW
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item model number:BP29693105
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8
The Ordinary8.5Good
The Ordinary Sulfur 10% Powder-to-Cream Acne Spot Treatment Concentrate, Reduces Pimple Size and Zit Redness, 0.18 Oz
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Mario Badescu8.4Good
Mario Badescu Drying Lotion for All Skin Types| Blemish Spot Treatment with Salicylic Acid and Sulfur | Dries Surface Blemishes | 1 Fl Oz
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is discontinued by manufacturer:No
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product dimensions:2.5 x 2.5 x 2 inches 1 ounces
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country of origin:USA
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upc:785364133082 785364130081 885790423518
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asin:B0017SWIU4
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10
Neutrogena8.3Good
Neutrogena Stubborn Acne Spot Drying Lotion, Fragrance-Free Sulfur Acne Treatment Clears Acne By Drying Up & Shrinking Pimples, Paraben- & Oil-Free, 10% Sulfur & 4% Niacinamide, 1.0 fl. oz
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is discontinued by manufacturer:N/A
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product dimensions:4.85 x 1.9 x 1.4 inches 2.75 ounces
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country of origin:USA
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upc:070501103227
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asin:B0B356WHD5
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