September 14, 2025

Advertising Disclosure

10 Best acid reflux supplements of 2025

Save up to 27% off

Best Choice

1

Gaia Herbs
Gaia Herbs Reflux Relief - with Marshmallow Root, Chamomile, Aloe, Licorice, and High Mallow - Helps with Occasional Heartburn and Relieve Indigestion - 45 Chewable Tablets (45-Day Supply)
Main highlights

Digestive Health Support
Contains organic marshmallow root, aloe, chamomile, licorice, and high mallow for effective heartburn and indigestion relief.

Ideal for Occasional Heartburn
Perfect for those seeking a natural alternative to traditional heartburn medications like ranitidine or Tums.

Quick and Lasting Relief
Praised by users for providing fast and enduring relief from digestive discomfort.
9.9

Exceptional

Our Rating

9.9
quality of ingredients

9.1
Comfort

8.7
pain management
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

LABO Nutrition
LABO Nutrition GASTRICELL - Acid Reflux, Heartburn, Recurring Gastric Discomfort, Natural Defence Against Gastric Distress 30 sachets

13% Off
Main highlights

Novel Probiotic Ingredient
GASTRICELL features L. johnsonii No. 1088 for gastric relief.

Ideal for Gastric Issues
Perfect for managing acid reflux, heartburn, and H. pylori.

Customer Praises Effectiveness
Praised for its impact on digestive health and comfort.
9.8

Exceptional

Our Rating

8.2
Flavor

8.0
worth the money
3

Zenwise Health
Zenwise Health Digestive Enzymes and Bromelain for Gut Health - Probiotic Multi Enzymes with Prebiotics and Probiotics for Women and Men for Digestive Health and Bloating Relief for Digestion - 60 CT
Main highlights

3-in-1 Gut Support
Digestive enzymes, probiotics, and prebiotics for holistic gut health.

Best for Diets and Bloating
Effective for gluten exposure, Keto, and Paleo diets.

Customer Praised Digestive Relief
Noticeable reduction in bloating and discomfort after meals.
Key specs
- Active Ingredients:Lactase, lipase, bromelain
- Usage:Gut support, digestive aid
- Formulation:Digestive Enzymes + Probiotics
- Features:3-in-1 gut support
- Dosage:1 capsule before meal
9.7

Exceptional

Our Rating

9.5
simple to consume

8.9
Absorbency

8.7
Flavor
4

Pure Encapsulations
Pure Encapsulations DGL Plus - Gut Health Supplements for Men & Women - with Marshmallow Root, Aloe Vera Extract & Slippery Elm Bark - Non-GMO & Vegan - 60 Capsules
Main highlights

Nutritional Support for Gut Health
Pure Encapsulations DGL Plus offers support for a healthy stomach lining and gastrointestinal tract with a blend of herbal extracts.

Ideal for GERD and Acid Reflux
Best used by individuals seeking relief from GERD and minor acid reflux, potentially as a substitute for medications.

Highly Effective for GERD Relief
Many customers report significant improvement in GERD symptoms and digestive health after using this product.
9.6

Exceptional

Our Rating

8.7
Flavor

8.7
worth the money
5

REFLUX GOURMET
REFLUX GOURMET Natural Heartburn Acid Reflux Relief Support Supplement for GERD, LPR, Indigestion, Aid for Intermittent Fasting, Alginate Therapy, Made in The USA, Vanilla Caramel
Main highlights

Natural Relief and Safe Ingredients
All-natural supplement for heartburn relief, free from glycerin, potassium, and parabens, safe for children and pregnancy.

Versatile Use for Reflux and Fasting
Ideal for those seeking relief from reflux, GERD, LPR, and hunger pains during intermittent fasting.

Customer Praised Taste and Effectiveness
Praised for effective relief and pleasant taste, with flavors like Vanilla Caramel and Mint Chocolate.
Key specs
- Form:Supplement
- Use:Heartburn relief
- Active Ingredient:Alginate
- Dosage:One teaspoon
- Flavor:Vanilla Caramel, Mint Chocolate
9.4

Excellent

Our Rating

9.7
Simple to use

9.5
simple to consume

9.3
Flavor
See Today’s Deals & Prices
6

Boiron
Boiron Acidil for Relief of Acid Reflux, Heartburn, Indigestion, and Upset Stomach - 60 Count

20% Off
Main highlights

Natural and Fast Relief
Boiron Acidil provides fast-acting relief from acid reflux, heartburn, and indigestion naturally.

Best for Mild Symptoms
Ideal for mild to moderate digestive discomforts, perfect for everyday use.

Quick-Dissolving Tablets
Customers appreciate the quick-dissolving tablets that work within minutes.
9.2

Excellent

Our Rating

8.0
Flavor

8.0
worth the money
7

Life Extension
Life Extension Esophageal Guardian, alginic Acid, Potassium Bicarbonate, get Long-Lasting Relief from gastric Distress, Vegetarian, Non-GMO, Gluten-Free, 60 Vegetarian chewable Tablets
Main highlights

Quick and Long-Lasting Relief
Esophageal Guardian offers immediate relief from gastric discomfort, lasting up to four hours.

Ideal for Reflux Sufferers
Perfect for those experiencing GERD, providing protection and relief.

Highly Praised Foam Raft Feature
Customers appreciate the foam raft that forms a protective barrier against reflux.
Key specs
- Calcium Content:Calcium carbonate
- Form:Gel
- Magnesium Content:Magnesium carbonate
- Flavor:Strawberry, pomegranate
- Vitamin D Content:N/A
9.1

Excellent

Our Rating

9.7
quality of ingredients

9.3
pain management

8.0
worth the money
8

Amazon Basic Care
Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1) (Packaging may vary)
Main highlights

Effective Acid Reduction
Omeprazole 20 mg reduces stomach acid, treating frequent heartburn occurring twice a week or more.

Recommended for Regular Heartburn Sufferers
Ideal for those experiencing heartburn at least twice weekly, requiring a 14-day treatment.

Cost-Effective Prilosec Alternative
Praised for affordability and effectiveness compared to Prilosec, offering great value.
8.9

Very Good

Our Rating

9.9
simple to consume

9.3
Flavor

9.3
worth the money
9

NOW Foods

NOW Foods Supplements, Acid Relief with Enzymes, Xylitol Sweetened, Digestive Health*, 60 Chewables

27% Off
8.8

Very Good

Our Rating
10

PRELIEF
Prelief Acid Reducer Caplets Dietary Supplement, 120 Count

20% Off
Main highlights

Effective_Acid_Reduction
Prelief caplets reduce up to 95% of acid from foods and drinks, providing significant relief from discomfort.

Ideal_for_Acid-Sensitive_Individuals
Best suited for those with acid sensitivity or conditions like interstitial cystitis, ensuring comfort during meals.

Customer_Praised_Versatility
Users appreciate its versatility in reducing acid in various foods, enhancing dining experiences.
8.6

Very Good

Our Rating

9.7
simple to consume

9.3
worth the money

9.1
Flavor

10 Best acid reflux supplements of 2025

1

Gaia Herbs Reflux Relief - with Marshmallow Root, Chamomile, Aloe, Licorice, and High Mallow - Helps with Occasional Heartburn and Relieve Indigestion - 45 Chewable Tablets (45-Day Supply)

9.9

9.1

8.7

How do we rank?

How do we rank?

Analyzing top stores

2

LABO Nutrition GASTRICELL - Acid Reflux, Heartburn, Recurring Gastric Discomfort, Natural Defence Against Gastric Distress 30 sachets

8.2

8.0

3

Zenwise Health Digestive Enzymes and Bromelain for Gut Health - Probiotic Multi Enzymes with Prebiotics and Probiotics for Women and Men for Digestive Health and Bloating Relief for Digestion - 60 CT

9.5

8.9

8.7

4

Pure Encapsulations DGL Plus - Gut Health Supplements for Men & Women - with Marshmallow Root, Aloe Vera Extract & Slippery Elm Bark - Non-GMO & Vegan - 60 Capsules

8.7

8.7

5

REFLUX GOURMET Natural Heartburn Acid Reflux Relief Support Supplement for GERD, LPR, Indigestion, Aid for Intermittent Fasting, Alginate Therapy, Made in The USA, Vanilla Caramel

9.7

9.5

9.3

6

Boiron Acidil for Relief of Acid Reflux, Heartburn, Indigestion, and Upset Stomach - 60 Count

8.0

8.0

7

Life Extension Esophageal Guardian, alginic Acid, Potassium Bicarbonate, get Long-Lasting Relief from gastric Distress, Vegetarian, Non-GMO, Gluten-Free, 60 Vegetarian chewable Tablets

9.7

9.3

8.0

8

Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1) (Packaging may vary)

9.9

9.3

9.3

9

NOW Foods Supplements, Acid Relief with Enzymes, Xylitol Sweetened, Digestive Health*, 60 Chewables

10

Prelief Acid Reducer Caplets Dietary Supplement, 120 Count

9.7

9.3

9.1

Sign up and get exclusive special deals