10 Best 5 htps of 2025

Save up to 48% off

Best Choice

1

THORNE
THORNE 5-Hydroxytryptophan (5-HTP) - Serotonin Support for Sleep and Stress Management* - 90 Capsules
Main highlights

Serotonin Support Benefit
Boosts serotonin levels to improve mood, sleep, and stress management.

Ideal for Sleep and Stress
Perfect for those seeking natural sleep aid and stress relief.

Customer Praised Mood Boost
Highly praised for enhancing mood and overall well-being.
9.7

Exceptional

Our Rating

9.9
Flavor

9.9
simple to consume

9.1
quality of ingredients
How do we rank?

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Based on millions of stores and reviews

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Value for Money

2

Clean Nutraceuticals
Clean Nutraceuticals GABA 750mg 5 HTP 200mg L Tryptophan 500mg L Theanine 200mg Ashwagandha SAM-e L-Glycine - Mood Support Vitamins for Women and Men with L-Tyrosine 5-HTP (5-Hydroxytryptophan)
Main highlights

Comprehensive Mood Support
Combines GABA, L-Theanine, Ashwagandha, 5-HTP, and L-Tryptophan for enhanced mood support and stress relief.

Ideal for Stress Relief
Perfect for reducing stress and promoting calmness, especially in high-pressure environments.

Highly Effective Sleep Aid
Praised for improving sleep quality and easing into restful nights.
9.5

Excellent

Our Rating
3

NOW Foods
NOW Foods Supplements, 5-HTP (5-hydroxytryptophan) 100 mg, Neurotransmitter Support*, 120 Veg Capsules

48% Off
Main highlights

Vegan Capsules and Neurotransmitter Support
5-HTP is the intermediate metabolite between L-tryptophan and serotonin, supporting serotonin production in the brain and central nervous system.

Ideal for Sleep and Mood Support
Typically used as a sleep supplement, 5-HTP supports positive mood, relaxation, appetite, and body temperature regulation.

Customer Praised for Improved Sleep Quality
Many users report better sleep quality, feeling more rested and less groggy, with noticeable mood improvements and reduced anxiety when taking 5-HTP.
9.3

Excellent

Our Rating

9.1
simple to consume

8.7
Flavor

8.0
quality of sleep
4

Nutricost
Nutricost 5-HTP 200mg, 120 Vegetarian Capsules (5-Hydroxytryptophan) - Non-GMO & Gluten Free
Main highlights

Key Features
High-potency 5-HTP in 200mg vegetarian capsules, non-GMO, gluten-free, and tested for purity by third-party labs for optimal quality assurance.

Ideal Use Cases
Perfect for those seeking mood enhancement, sleep support, and an overall boost in well-being, especially vegetarians and individuals with dietary restrictions.

Customer Praise
Most reviews highlight its effectiveness in improving sleep patterns and enhancing mood, with many appreciating the vegetarian capsule form.
9.0

Excellent

Our Rating

8.7
simple to consume

8.2
worth the money

8.0
quality of sleep
5

Natures Craft

5 HTP Supplement 5-Hydroxytryptophan - 5HTP 100mg per Serving Gentle Herbal Sleep and Mood Enhancer - 5-HTP 100 mg per Serving Mood Supplement and Sleep Support Capsules from Griffonia Simplicifolia
8.9

Very Good

Our Rating
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6

NOW Foods
NOW Foods Supplements, 5-HTP (5-hydroxytryptophan) 100 mg, Neurotransmitter Support*, 60 Veg Capsules

43% Off
Main highlights

Vegan Neurotransmitter Support
5-HTP is a vegan supplement that supports serotonin production, impacting sleep, mood, appetite, and body temperature. It is Non-GMO, gluten-free, and GMP certified.

Ideal for Sleep and Mood Enhancement
5-HTP is typically used to improve sleep quality and support positive mood and relaxation, making it ideal for those with anxiety, depression, or sleep issues.

Praised for Mood Improvement
Customers frequently commend 5-HTP for its significant positive impact on mood, reducing anxiety and depression, and improving overall mental well-being.
8.7

Very Good

Our Rating

9.9
Flavor

9.9
simple to consume

8.7
worth the money
7

Nutricost
Nutricost 5-HTP 100mg, 240 Vegetarian Capsules (5-Hydroxytryptophan) - Non-GMO & Gluten Free
Main highlights

Key Features
Nutricost`s 5-HTP offers a potent 100mg per serving, lasting up to 8 months, with a vegetarian, non-GMO, and gluten-free formula.

Ideal Use
Perfect for individuals seeking to enhance well-being, manage stress, and improve sleep quality, integrating seamlessly into daily health routines.

Customer Praise
Reviews highly commend its effectiveness in improving mood and sleep, noting significant wellness benefits with consistent use.
8.4

Good

Our Rating

9.3
worth the money

9.1
simple to consume

8.7
Flavor
8

Triquetra Health
Organic 5-HTP - 200 mg | 99% 5HTP Concentration, Plus Cofactor Vitamin B6 & Lion’s Mane | Water Extracted from Organic Griffonia Seeds | Supports Mood, Cognition & Sleep (60 Capsules | 30 Servings)
Main highlights

Purest Source of 5-HTP
Organic 5-HTP derived from Griffonia Seeds, extracted using water, ensuring no chemical residues, with a 99% purity for maximum efficacy.

Ideal for Mood and Sleep Support
Perfect for promoting a calm mood, better sleep quality, and enhanced mental cognition, making it suitable for those seeking natural relaxation and improved mental health.

Highly Praised Sleep Improvement
Customers frequently highlight improved sleep quality and feeling well-rested, contributing to better daily energy and mood balance.
8.3

Good

Our Rating
9

DR. EMIL NUTRITION
DR. EMIL NUTRITION 200 MG 5-HTP Plus with SAM-e to Maintain Normal Healthy Sleep and Create a Sense of Wellbeing - 5HTP Supplement with Vitamin B6-60 Vegan Capsules, 30 Servings
Main highlights

Mood and Sleep Support
Combines 200mg 5-HTP with SAMe and Vitamin B6 for mood enhancement and restful sleep.

Ideal for Anxiety Relief
Perfect for individuals seeking natural support for anxiety, mood balance, and sleep improvement.

Praised for Sleep Improvement
Customers frequently commend its ability to enhance sleep quality and emotional wellbeing.
8.0

Good

Our Rating

9.7
simple to consume

9.7
Flavor

9.5
quality of ingredients
10

Double Wood Supplements
5HTP Liquid Drops - More Absorbable and Effective Than 5 HTP Capsules (60 Servings of 50mg 99%+ 5-HTP) Serotonin Supplement for Mood, Sleep, and Relaxation by Double Wood
Main highlights

Superior Absorption
Liquid form ensures maximum absorption, outperforming traditional capsules.

Mood and Relaxation Support
Ideal for improving mood and promoting relaxation in stressful times.

Positive Customer Feedback
Praised for effective mood enhancement and non-offensive taste.
7.8

Good

Our Rating

8.9
Flavor

8.4
Simple to use

8.2
quality of sleep

10 Best 5 htps of 2025

1

THORNE 5-Hydroxytryptophan (5-HTP) - Serotonin Support for Sleep and Stress Management* - 90 Capsules

9.9

9.9

9.1

How do we rank?

How do we rank?

Analyzing top stores

2

Clean Nutraceuticals GABA 750mg 5 HTP 200mg L Tryptophan 500mg L Theanine 200mg Ashwagandha SAM-e L-Glycine - Mood Support Vitamins for Women and Men with L-Tyrosine 5-HTP (5-Hydroxytryptophan)

3

NOW Foods Supplements, 5-HTP (5-hydroxytryptophan) 100 mg, Neurotransmitter Support*, 120 Veg Capsules

9.1

8.7

8.0

4

Nutricost 5-HTP 200mg, 120 Vegetarian Capsules (5-Hydroxytryptophan) - Non-GMO & Gluten Free

8.7

8.2

8.0

5

5 HTP Supplement 5-Hydroxytryptophan - 5HTP 100mg per Serving Gentle Herbal Sleep and Mood Enhancer - 5-HTP 100 mg per Serving Mood Supplement and Sleep Support Capsules from Griffonia Simplicifolia

6

NOW Foods Supplements, 5-HTP (5-hydroxytryptophan) 100 mg, Neurotransmitter Support*, 60 Veg Capsules

9.9

9.9

8.7

7

Nutricost 5-HTP 100mg, 240 Vegetarian Capsules (5-Hydroxytryptophan) - Non-GMO & Gluten Free

9.3

9.1

8.7

8

Organic 5-HTP - 200 mg | 99% 5HTP Concentration, Plus Cofactor Vitamin B6 & Lion’s Mane | Water Extracted from Organic Griffonia Seeds | Supports Mood, Cognition & Sleep (60 Capsules | 30 Servings)

9

DR. EMIL NUTRITION 200 MG 5-HTP Plus with SAM-e to Maintain Normal Healthy Sleep and Create a Sense of Wellbeing - 5HTP Supplement with Vitamin B6-60 Vegan Capsules, 30 Servings

9.7

9.7

9.5

10

5HTP Liquid Drops - More Absorbable and Effective Than 5 HTP Capsules (60 Servings of 50mg 99%+ 5-HTP) Serotonin Supplement for Mood, Sleep, and Relaxation by Double Wood

8.9

8.4

8.2

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