9 Best 1mg l 5 mthfs of 2026

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Best Choice

1

Designs for Health
Designs for Health L 5-MTHF - Quatrefolic L Methylfolate Supplement 1mg (1700mcg DFE) - Methylated Folate Supplement for Women & Men - Supports Methylation - Non-GMO, Gluten Free (120 Capsules)
Main highlights

Bio-Active Folate for Brain and Energy Support
L-5-MTHF provides folate in the bioidentical, bioactive form 5-methyltetrahydrofolate, supporting brain function, energy levels, and healthy homocysteine pathways.

Ideal for Individuals with MTHFR Gene Mutation
L-5-MTHF is perfect for those who cannot process standard folic acid, offering high bioavailability and stability, essential for methylation and overall health.

Highly Recommended by Functional Medicine Professionals
Praised for its quality and effectiveness, this supplement is trusted by both allergists and gynecologists, making it a top choice among practitioners.
Key specs
- Form:Capsule
- Active Ingredient:5-methyltetrahydrofolate
- Bioavailability:High bioavailability
- Dosage:1mg per capsule
- Serving Size:1 capsule
9.8

Exceptional

Our Rating

9.9
quality of ingredients

9.3
materials Quality

8.2
worth the money
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Value for Money

2

Designs for Health
Designs for Health L 5-MTHF - Quatrefolic L Methylfolate Supplement 1mg (1700mcg DFE) - Methylated Folate Supplement for Women & Men - Supports Methylation - Non-GMO, Gluten Free (120 Capsules)
Main highlights

Bio-Active Folate for Brain and Energy Support
L-5-MTHF provides folate in the bioidentical, bioactive form 5-methyltetrahydrofolate, supporting brain function, energy levels, and healthy homocysteine pathways.

Ideal for Individuals with MTHFR Gene Mutation
L-5-MTHF is perfect for those who cannot process standard folic acid, offering high bioavailability and stability, essential for methylation and overall health.

Highly Recommended by Functional Medicine Professionals
Praised for its quality and effectiveness, this supplement is trusted by both allergists and gynecologists, making it a top choice among practitioners.
Key specs
- Form:Capsule
- Active Ingredient:5-methyltetrahydrofolate
- Bioavailability:High bioavailability
- Dosage:1mg per capsule
- Serving Size:1 capsule
9.6

Exceptional

Our Rating

9.9
quality of ingredients

9.3
materials Quality

8.2
worth the money
3

Nature's Fusions
Nature's Fusions Nutri 5-MTHF L Methylfolate 1MG - 4 Month Supply, 120 Vegan Tablets - Methylated Folate Supplement - Cognitive Function, Heart Health, Prenatal Support - Methylated Folic Acid

23% Off
Main highlights

Potent Methylated Folate Formula
Delivers 1MG per serving, supporting energy, DNA synthesis, and neurotransmitter regulation.

Ideal for Methylation Support
Optimizes methylation for cardiovascular health, cognitive function, and prenatal support.

Vegan-Friendly and Easy to Swallow
Praised for being vegan-friendly, easy to swallow, with no aftertaste.
Key specs
- Form:Vegan tablets
- Active Ingredient:5-MTHF
- Bioavailability:High
- Dosage:1 MG per serving
- Serving Size:1 tablet
9.5

Excellent

Our Rating
4

Nature's Fusions
Nature's Fusions Nutri 5-MTHF L Methylfolate 1MG - 4 Month Supply, 120 Vegan Tablets - Methylated Folate Supplement - Cognitive Function, Heart Health, Prenatal Support - Methylated Folic Acid

31% Off
Main highlights

Potent Methylated Folate Formula
Delivers 1MG per serving, supporting energy, DNA synthesis, and neurotransmitter regulation.

Ideal for Methylation Support
Optimizes methylation for cardiovascular health, cognitive function, and prenatal support.

Vegan-Friendly and Easy to Swallow
Praised for being vegan-friendly, easy to swallow, with no aftertaste.
Key specs
- Form:Vegan tablets
- Active Ingredient:5-MTHF
- Bioavailability:High
- Dosage:1 MG per serving
- Serving Size:1 tablet
9.4

Excellent

Our Rating
5

THORNE
THORNE - 5-MTHF - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation & Homocysteine Levels* - 60 Servings - 5-MTHF 1mg
Main highlights

Supports Cardiovascular and Nerve Health
Thorne 5-MTHF provides active folate for cardiovascular, nerve health, and methylation support.

Ideal for MTHFR Gene Mutation
Perfect for individuals with MTHFR mutation needing enhanced folate absorption.

Improves Focus and Mood
Customers praise its ability to enhance focus, mood, and overall well-being.
9.3

Excellent

Our Rating

9.9
simple to consume

9.5
Absorbency

9.3
worth the money
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6

THORNE
THORNE - 5-MTHF - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation & Homocysteine Levels* - 60 Servings - 5-MTHF 1mg

10% Off
Main highlights

Supports Cardiovascular and Nerve Health
Thorne 5-MTHF provides active folate for cardiovascular, nerve health, and methylation support.

Ideal for MTHFR Gene Mutation
Perfect for individuals with MTHFR mutation needing enhanced folate absorption.

Improves Focus and Mood
Customers praise its ability to enhance focus, mood, and overall well-being.
9.2

Excellent

Our Rating

9.9
simple to consume

9.5
Absorbency

9.3
worth the money
7

Carlyle

Carlyle 5-MTHF L Methylfolate 1mg | 120 Capsules | Non-GMO & Gluten Free Supplement | Premium Quality
8.9

Very Good

Our Rating
8

Carlyle

Carlyle 5-MTHF L Methylfolate 1mg | 120 Capsules | Non-GMO & Gluten Free Supplement | Premium Quality

10% Off
8.6

Very Good

Our Rating
9

Triquetra Health

L Methyl Folate 1000 mcg Plus Methyl B12 Cofactor – Active 5-MTHF Form - Supports Mood, Methylation, Cognition – Highly Bioavailable Bioactive Forms of Vitamin B9 & B12 (60 Capsules – 60 Servings)
8.4

Good

Our Rating

9 Best 1mg l 5 mthfs of 2026

1

Designs for Health L 5-MTHF - Quatrefolic L Methylfolate Supplement 1mg (1700mcg DFE) - Methylated Folate Supplement for Women & Men - Supports Methylation - Non-GMO, Gluten Free (120 Capsules)

9.9

9.3

8.2

How do we rank?

How do we rank?

Analyzing top stores

2

Designs for Health L 5-MTHF - Quatrefolic L Methylfolate Supplement 1mg (1700mcg DFE) - Methylated Folate Supplement for Women & Men - Supports Methylation - Non-GMO, Gluten Free (120 Capsules)

9.9

9.3

8.2

3

Nature's Fusions Nutri 5-MTHF L Methylfolate 1MG - 4 Month Supply, 120 Vegan Tablets - Methylated Folate Supplement - Cognitive Function, Heart Health, Prenatal Support - Methylated Folic Acid

4

Nature's Fusions Nutri 5-MTHF L Methylfolate 1MG - 4 Month Supply, 120 Vegan Tablets - Methylated Folate Supplement - Cognitive Function, Heart Health, Prenatal Support - Methylated Folic Acid

5

THORNE - 5-MTHF - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation & Homocysteine Levels* - 60 Servings - 5-MTHF 1mg

9.9

9.5

9.3

6

THORNE - 5-MTHF - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation & Homocysteine Levels* - 60 Servings - 5-MTHF 1mg

9.9

9.5

9.3

7

Carlyle 5-MTHF L Methylfolate 1mg | 120 Capsules | Non-GMO & Gluten Free Supplement | Premium Quality

8

Carlyle 5-MTHF L Methylfolate 1mg | 120 Capsules | Non-GMO & Gluten Free Supplement | Premium Quality

9

L Methyl Folate 1000 mcg Plus Methyl B12 Cofactor – Active 5-MTHF Form - Supports Mood, Methylation, Cognition – Highly Bioavailable Bioactive Forms of Vitamin B9 & B12 (60 Capsules – 60 Servings)

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